Active Studies

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A-PLUS

Current Research: A randomized, placebo-controlled, parallel multicenter clinic trial to assess whether a single, prophylactic intrapartum oral dose of 2g azithromycin given to women in labor will reduce (1) maternal death or sepsis and (2) intrapartum/neonatal death or sepsis.

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MATERNAL NEWBORN HEALTH REGISTRY

Current Research: A prospective, population-based pregnancy study in low-middle income countries. Sites enroll pregnant women and follow 6 weeks post-delivery. Enrolling 60,000 women/year, MNH quantifies services, and provides stillbirth, neonatal and maternal mortality rates to inform research.

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MNHR COVID SUB-STUDY

Current Research: The MNHR COVID study will determine the prevalence of COVID-19 antibodies in pregnant /recently delivered women in 8 Global Network sites (in DRC, Kenya, Zambia, Bangladesh, India [2 sites], Pakistan and Guatemala) and its association with maternal, fetal and neonatal outcomes. Additionally, we aim to explore knowledge, attitudes and prevention practices regarding COVID-19 during pregnancy.

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ASPIRIN NEURODEVELOPMENT FOLLOW-UP

Current Research: A total of 620 children will be enrolled in this study from six sites in sub-Saharan Africa, South Asia, and Latin America. Half of the children's mothers will have taken aspirin and half will have taken placebo. This will allow the researchers to compare results of the two groups of children and determine if children exposed antenatally to low dose aspirin will have no significant difference in neurodevelopmental behavior than those of their peers.

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